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Deposition of Inhaled Particles in Lungs

Nature volume 221, pages 661–662 (1969)Cite this article

Abstract

Davies and Muir1 and Dennis2 have reviewed the differences existing in experimental results relating particle size and deposition in the human lung. Data from six independent studies spanning 25 yr fell into two ranges, three groups of workers obtaining much higher values for deposition than the other three for particles greater than 0.5 microns in diameter. Interpretation of these results still seems to be a matter of opinion. Davies and Muir suggested that a sampling error of the exhaled air could give rise to the difference. Dennis, in reply, shows that the sampling error was not involved but that the difference may be the result of differences in nasal and oral breathing.

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References

  1. Davies, C. N., and Muir, D. C., Nature, 211, 90 (1966).

    Article  ADS  CAS  Google Scholar 

  2. Dennis, W. L., Nature, 214, 908 (1967).

    Article  ADS  CAS  Google Scholar 

  3. National Academy of Sciences—National Research Council Publ. No. 848, 28 (1961).

  4. Hlth Phys., 12, 173 (1966).

  5. Wilson, I. B., and La Mer, V. K., J. Indust. Hyg. Toxicol., 30, 265 (1948).

    CAS  Google Scholar 

  6. Brown, J. H., Cook, K. M., Ney, F. G., and Hatch, T., Amer. J. Pub. Hlth, 40, 450 (1950).

    Article  CAS  Google Scholar 

  7. Landahl, H. D., Tracewell, T. N., and Lassen, W. H., Arch. Indust. Hyg., 3, 359 (1951).

    CAS  Google Scholar 

  8. Altshuler, B., Yarmus, L., Palmes, E. D., and Nelson, N., Amer. Med. Assoc. Arch. Indust. Hlth, 15, 293 (1957).

    CAS  Google Scholar 

  9. Dautrebande, L., Beckmann, H., and Walkenhorst, W., Amer. Med. Assoc. Arch. Indust. Hlth, 16, 179 (1957).

    CAS  Google Scholar 

  10. Muir, D. C. F., and Davies, C. N., Ann. Occup. Hyg., 10, 161 (1967).

    PubMed  CAS  Google Scholar 

  11. Vaughan, W. J., and Vaughan, B. E., Naval Radiological Defense Laboratory Tech. Rep., TR-68-108).

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Authors and Affiliations

  1. Biological and Medical Sciences Division, Naval Radiological Defense Laboratory, San Francisco, California, 94135

    WILLIAM J. VAUGHAN & BURTON E. VAUGHAN

Authors
  1. WILLIAM J. VAUGHAN
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  2. BURTON E. VAUGHAN
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VAUGHAN, W., VAUGHAN, B. Deposition of Inhaled Particles in Lungs. Nature 221, 661–662 (1969). https://doi.org/10.1038/221661b0

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