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Structure–Activity Relationships of One-Ring Psychotomimetics

Abstract

Human dose-response relationships for psychotomimetic phenethylamines : an isopropylamine side chain and triple methoxy substitution provide optimum activity. Available data suggest possible structures for the hypothetical psychotogen of schizophrenia.

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SHULGIN, A., SARGENT, T. & NARANJO, C. Structure–Activity Relationships of One-Ring Psychotomimetics. Nature 221, 537–541 (1969). https://doi.org/10.1038/221537a0

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