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Behaviour of Infectious RNA from Four Different Viruses in Continuously Subcultured Aedes aegypti Mosquito Embryo Cells

Abstract

ONE of the characteristics of arboviruses is their capacity to propagate in insect vectors, although insects are refractory to other RNA viruses1. I have already shown that mosquito tissue culture, like intact mosquitoes, can support the proliferation of various group A and group B arboviruses2,3. Attempts to propagate encephalomyocarditis (EMC) and polio picornaviruses in mosquito tissue culture gave consistently negative results, similar to the in vivo situation. These results were not affected by the use of DEAE dextran, a substance which has been shown to affect the susceptibility of mice to a non-pathogenic variant of EMC virus4.

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References

  1. Andrews, C. H., Adv. Virus Res., 9, 271 (1962).

    Article  Google Scholar 

  2. Peleg, J., Amer. J. Trop. Med. Hyg., 17, 219 (1968).

    Article  CAS  Google Scholar 

  3. Peleg, J., Virology, 35, 617 (1968).

    Article  CAS  Google Scholar 

  4. Craighead, J. E., J. Virol., 1, 988 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Holland, J. J., McLaren, L. C., and Syverton, J. T., J. Exp. Med., 110, 65 (1959).

    Article  CAS  Google Scholar 

  6. Bellett, A. J. D., Bumess, A. T. H., and Sanders, F. K., Nature, 195, 874 (1962).

    Article  ADS  CAS  Google Scholar 

  7. Reed, L. J., and Muench, H., Amer. J. Hyg., 27, 493 (1938).

    Google Scholar 

  8. Nakamura, M., and Ueno, Y., Proc. Soc. Exp. Biol. and Med., 113, 1037 (1963).

    Article  CAS  Google Scholar 

  9. Amstey, M. S., and Parkman, P. D., Proc. Soc. Exp. Biol. and Med., 123, 438 (1966).

    Article  CAS  Google Scholar 

  10. Pagano, J. S., McCutchan, J. H., and Vaheri, A., J. Virol., 1, 891 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

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PELEG, J. Behaviour of Infectious RNA from Four Different Viruses in Continuously Subcultured Aedes aegypti Mosquito Embryo Cells. Nature 221, 193–194 (1969). https://doi.org/10.1038/221193a0

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