Abstract
THE decapeptide angiotensin I is converted to an octapeptide angiotensin II by a plasma enzyme named the converting enzyme1. Bumpus et al.2 proposed the liver as a probable site of synthesis for the plasma enzyme, but it has recently been reported that angiotensin I is converted to angiotensin II in the vascular bed of the lung3. These investigators3 postulated that “the converting enzyme may be located on or in the pulmonary cells”.
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CARRETERO, O., BUMPUS, F. & SMEBY, R. Pressor Response to Angiotensins I and II and Renin in Rats treated with Carbon Tetrachloride. Nature 221, 1067–1068 (1969). https://doi.org/10.1038/2211067a0
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DOI: https://doi.org/10.1038/2211067a0
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