Abstract
THE HL-A system of leucocyte antigens and the ABH red cell groups are believed to be important histocompatibility factors in man1 and can be detected on leucocytes, platelets and most other tissues2. Although A1 and B antigens have been demonstrated on leucocytes, attempts to detect HL-A specificities on red cells have so far failed3. The apparent absence of HL-A from human red cells is unlike the situation found in the mouse where H-2 antigens, the homologues of HL-A, can usually be demonstrated on red cells4. It is logical that human red cell precursors should possess HL-A antigens and we have therefore investigated reticulocytes by absorption studies, which does not seem to have been done before (van Rood, personal communication).
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References
Dausset, J., and Rapaport, F. T., Human Transplantation, 383 (Grune and Stratton, New York and London, 1968).
Bruning, J. W., van Leeuwen, A., and van Rood, J. J., Proc. Ninth Cong. Intern. Soc. Blood Transfusion, Mexico, 569 (Karger, Basle and New York, 1962).
Dausset, J., and Rapaport, F. T., Human Transplantation, 369 (Grune and Stratton, New York and London, 1968).
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Dausset, J., and Tangün, Y., Vox Sang., 10, 641 (1965).
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HARRIS, R., ZERVAS, J. Reticulocyte HL-A Antigens. Nature 221, 1062–1063 (1969). https://doi.org/10.1038/2211062a0
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DOI: https://doi.org/10.1038/2211062a0
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