Abstract
THE analysis of the effects of single genes on behaviour may yield information not only about the genetics of behavioral characters, but about the characters themselves1. When, however, data are collected on segregating populations for a few generations apparent single gene effects may be due to the effects of closely linked loci, especially when these populations are derived from an initial cross of parental strains which differ widely in the character in question. Thus when apparent major-gene effects are found, it is important to verify that such effects are truly pleiotropic.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Merrell, D. J., J. Hered., 56, 263 (1965).
DeFries, J. C., Hegmann, J. P., and Weir, M. W., Science, 154, 1577 (1966).
DeFries, J. C., and Hegmann, J. P., in Contributions to Behaviour-Genetic Analysis: The Mouse as a Prototype (edit. by Lindzey, G., and Thiessen. D. D.) (in the press).
Henry, K. R., and Schlesinger, K., J. Comp. Physiol. Psychol., 63, 320 (1967).
Fuller, J. L., Animal Behav., 15, 467 (1967).
van Abeelen, J. H. F., and Kroes, H. W., Genetica, 38, 419 (1967).
McReynolds, W. E., Weir, M. W., DeFries, J. C., Psychonom. Sci., 9, 277 (1967).
Dixon, L. K., and DeFries, J. C., J. Comp. Physiol. Psychol. (in the press).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DEFRIES, J. Pleiotropic Effects of Albinism on Open Field Behaviour in Mice. Nature 221, 65–66 (1969). https://doi.org/10.1038/221065a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/221065a0
This article is cited by
-
Gene networks associated with conditional fear in mice identified using a systems genetics approach
BMC Systems Biology (2011)
-
Genomic mapping of social behavior traits in a F2 cross derived from mice selectively bred for high aggression
BMC Genetics (2010)
-
Rapid Selection Response for Contextual Fear Conditioning in a Cross Between C57BL/6J and A/J: Behavioral, QTL and Gene Expression Analysis
Behavior Genetics (2008)
-
Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains
Behavior Genetics (1995)
-
Use of recombinant inbred strains to detect quantitative trait loci associated with behavior
Behavior Genetics (1991)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.