Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Pleiotropic Effects of Albinism on Open Field Behaviour in Mice

Abstract

THE analysis of the effects of single genes on behaviour may yield information not only about the genetics of behavioral characters, but about the characters themselves1. When, however, data are collected on segregating populations for a few generations apparent single gene effects may be due to the effects of closely linked loci, especially when these populations are derived from an initial cross of parental strains which differ widely in the character in question. Thus when apparent major-gene effects are found, it is important to verify that such effects are truly pleiotropic.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Merrell, D. J., J. Hered., 56, 263 (1965).

    Article  CAS  Google Scholar 

  2. DeFries, J. C., Hegmann, J. P., and Weir, M. W., Science, 154, 1577 (1966).

    Article  ADS  CAS  Google Scholar 

  3. DeFries, J. C., and Hegmann, J. P., in Contributions to Behaviour-Genetic Analysis: The Mouse as a Prototype (edit. by Lindzey, G., and Thiessen. D. D.) (in the press).

  4. Henry, K. R., and Schlesinger, K., J. Comp. Physiol. Psychol., 63, 320 (1967).

    Article  CAS  Google Scholar 

  5. Fuller, J. L., Animal Behav., 15, 467 (1967).

    Article  CAS  Google Scholar 

  6. van Abeelen, J. H. F., and Kroes, H. W., Genetica, 38, 419 (1967).

    Article  Google Scholar 

  7. McReynolds, W. E., Weir, M. W., DeFries, J. C., Psychonom. Sci., 9, 277 (1967).

    Article  Google Scholar 

  8. Dixon, L. K., and DeFries, J. C., J. Comp. Physiol. Psychol. (in the press).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

DEFRIES, J. Pleiotropic Effects of Albinism on Open Field Behaviour in Mice. Nature 221, 65–66 (1969). https://doi.org/10.1038/221065a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/221065a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing