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Effect of Actinomycin D on the Assimilation of a Cytoplasmic Determinant in Amoebae

Nature volume 220, pages 923–924 (1968)Cite this article

Abstract

CERTAIN cellular properties of the large free living amoebae, Amoeba proteus and Amoeba discoides, such as sensitivity to streptomycin and nuclear diameter, have been shown to be influenced by self-replicating cyto-plasmic hereditary determinants1. A. proteus is more sensitive to streptomycin and has a greater nuclear diameter than A. discoides2,3. Micro-injection of small quantities of cytoplasm of A. discoides into recipient A. proteus results in the transfer and expression of the determinant studied—for example, lowered sensitivity to streptomycin—for a small fraction of the clones derived from cells surviving the operation1.

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Authors and Affiliations

  1. Department of Zoology, King's College, University of London,

    SHIRLEY E. HAWKINS

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  1. SHIRLEY E. HAWKINS
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HAWKINS, S. Effect of Actinomycin D on the Assimilation of a Cytoplasmic Determinant in Amoebae. Nature 220, 923–924 (1968). https://doi.org/10.1038/220923b0

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  • DOI: https://doi.org/10.1038/220923b0

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