Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Miraculin, the Sweetness-inducing Protein from Miracle Fruit


THE berries of Richardella dulcifica (Schum. and Thonn.) Baehni, formerly designated as Synsepalum dulcificum1, a shrub indigenous to tropical West Africa, have long been known for their taste-changing properties2. These berries, called miraculous berries or miracle fruit, have the property of modifying the taste of sour foods and dilute mineral and organic acids into a sweet taste after the fruit pulp has been chewed. This modifying effect lasts for some time, usually for 1–2 h.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others


  1. Baehni, C., Boissiera, 11, 1 (1965).

    Google Scholar 

  2. Daniell, W. F., Pharm. J., 11, 445 (1852).

    Google Scholar 

  3. Inglett, G. E., Dowling, B., Albrecht, J. J., and Hoglan, F. A., J. Agric. Food Chem., 13, 284 (1965).

    Article  CAS  Google Scholar 

  4. Badran, A. M., and Jones, D. E., Nature, 206, 622 (1965).

    Article  ADS  CAS  Google Scholar 

  5. Goldstein, J. L., and Swain, T., Phytochemistry, 4, 185 (1965).

    Article  CAS  Google Scholar 

  6. Hultin, H. O., and Levine, A. S., J. Food Sci., 30, 917 (1965).

    Article  CAS  Google Scholar 

  7. Reisfeld, R. A., Lewis, U. J., and Williams, D. E., Nature, 195, 281 (1962).

    Article  ADS  CAS  Google Scholar 

  8. Scott, T. A., and Melvin, E. H., Anal. Chem., 25, 1656 (1953).

    Article  CAS  Google Scholar 

  9. Garin, S., and Hood, D. B., J. Biol. Chem., 131, 211 (1939).

    Google Scholar 

  10. Beidler, L. M., J. Food Sci., 31, 275 (1966); Sci. News Lett., 88, 329 (1965).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

BROUWER, J., VAN DER WEL, H., FRANCKE, A. et al. Miraculin, the Sweetness-inducing Protein from Miracle Fruit. Nature 220, 373–374 (1968).

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing