Role of Different RNA Fractions from the Brain in Transfer Effect


IN an earlier report1 we demonstrated an optimal transfer effect of learning in rats when donors were trained for 10 days (twelve experimental sessions) and when adult recipients were not habituated to the conditional stimulus. The transfer problem seems to be very important as far as an understanding of the mechanisms of memory storage is concerned; we thus continued our investigations with rats to determine whether the successful transfer phenomenon is reproducible after destruction of brain RNA and, if not, which fraction of the brain RNA is responsible for the successful effect.

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  1. 1

    Adám, G., and Faiszt, J., Nature, 216, 198 (1967).

  2. 2

    Kimberlin, R. H., J. Neurochem., 14, 123 (1967).

  3. 3

    Wilcoxon, F., and Wilcox, R. A., Some Rapid Approximate Statistical Procedures (Lederle, Pearl River, NY, 1964).

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FAISZT, J., ADÁM, G. Role of Different RNA Fractions from the Brain in Transfer Effect. Nature 220, 367–368 (1968).

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