Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cellular and Humoral immunity to Different Types of Human Neoplasms


MOST experimentally induced animal neoplasms contain tumour specific transplantation antigens (TSTA), against which immunological reactions can be detected both in vivo and in vitro1–5.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type



Prices may be subject to local taxes which are calculated during checkout


  1. Old, L. J., and Boyse, E. A., Ann. Rev. Med., 15, 167 (1964).

    Article  CAS  Google Scholar 

  2. Sjögren, H. O., Prog. Exp. Tumor Res., 6, 289 (1965).

    Article  Google Scholar 

  3. Klein, G., Ann. Rev. Microbiol., 20, 223 (1966).

    Article  CAS  Google Scholar 

  4. Mikulska, Z. B., Smith, C., and Alexander, P., J. Nat. Cancer Inst., 36, 29 (1966).

    CAS  Google Scholar 

  5. Rosenau, W., and Morton, D., J. Nat. Cancer Inst., 36, 825 (1966).

    Google Scholar 

  6. Hellström, I., and Sjögren, H. O., Exp. Cell Res., 40, 212 (1965).

    Article  Google Scholar 

  7. Hellström, I., Intern. J. Cancer, 2, 65 (1967).

    Article  Google Scholar 

  8. Hellström, I., Nature, 208, 652 (1965).

    Article  ADS  Google Scholar 

  9. Hellström, I., and Sjögren, H. O., J. Exp. Med., 125, 1105 (1967).

    Article  Google Scholar 

  10. Hellström, I., and Hellström, K. E., Science, 156, 981 (1967).

    Article  ADS  Google Scholar 

  11. Hellström, I., Hellström, K. E., and Pierce, G., Intern. J. Cancer, 3, 467 (1968).

    Article  Google Scholar 

  12. Hellström, I., Hellström, K. E., Pierce, G. E., and Bill, A. H., Proc. US Nat. Acad. Sci., 60, 1231 (1968).

    Article  ADS  Google Scholar 

  13. Klein, G., Clifford, P., Klein, E., and Stjernswärd, J., Proc. US Nat. Acad. Sci., 55, 1628 (1966).

    Article  ADS  CAS  Google Scholar 

  14. Gold, P., and Freedman, S. O., J. Exp. Med., 121, 439 (1965).

    Article  CAS  Google Scholar 

  15. Gold, P., and Freedman, S. O., J. Exp. Med., 122, 467 (1965).

    Article  CAS  Google Scholar 

  16. Morton, D. L., Malmgren, R. A., Holmes, E. C., and Ketcham, A. S., Surgery, 64, 233 (1968).

    PubMed  CAS  Google Scholar 

  17. Chu, E., Stjernswärd, J., Clifford, P., and Klein, G., J. Nat. Cancer Inst., 39, 595 (1967).

    PubMed  CAS  Google Scholar 

  18. Lewis, M. G., Lancet, ii, 921 (1967).

  19. Southam, C. M., Prog. Exp. Tumor Res., 9, 1 (1967).

    Article  CAS  Google Scholar 

  20. Stjernswärd, J., East Afric. Med. J., 45, 484 (1968).

    Google Scholar 

  21. Everson, T. C., and Cole, W. H., Spontaneous Regression of Cancer, 560 (Saunders, Philadelphia, 1966).

    Google Scholar 

  22. Ming, S. C., Klein, E., and Klein, G., Nature, 215, 1390 (1967).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

HELLSTRÖM, I., HELLSTRÖM, K., PIERCE, G. et al. Cellular and Humoral immunity to Different Types of Human Neoplasms. Nature 220, 1352–1354 (1968).

Download citation

  • Received:

  • Issue Date:

  • DOI:

This article is cited by


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing