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Tremorgenic Toxin from Penicillium cyclopium grown on Food Materials

Nature volume 220, pages 77–78 (1968)Cite this article

Abstract

DRUGS and other compounds capable of causing sustained trembling are rare; in a survey of ten thousand compounds Everett et al. found less than ten with this property1. One of the best known is tremorine (1,4-dipyrrolidine-2-butyne) which is converted into a more active compound, oxotremorine2, by body tissues. Various synthetic amino alcohols also stimulate prolonged tremors, but their mechanism of action differs from that of tremorine and other more familiar compounds3.

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References

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Authors and Affiliations

  1. Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee

    BENJAMIN J. WILSON, CHRISTINA H. WILSON & A. WALLACE HAYES

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  1. BENJAMIN J. WILSON
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  2. CHRISTINA H. WILSON
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  3. A. WALLACE HAYES
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WILSON, B., WILSON, C. & HAYES, A. Tremorgenic Toxin from Penicillium cyclopium grown on Food Materials. Nature 220, 77–78 (1968). https://doi.org/10.1038/220077b0

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  • DOI: https://doi.org/10.1038/220077b0

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