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Possible Mechanism for Mycoplasma Inhibition of Lymphocyte Transformation induced by Phytohaemagglutinin

Nature volume 219, pages 751–752 (1968)Cite this article

Abstract

Mycoplasma pneumoniae stimulates transformation and mitosis in cultures of lymphocytes obtained from sensitized individuals1, as do other antigens2. In contrast, M. hominis3 and M. arthritidis4 inhibit lymphocyte transformation induced by phytohaemagglutinin (PHA). We have examined the effects of different species of Mycoplasma on lymphocyte cultures in an attempt to elucidate the mechanism of mycoplasma inhibition of PHA-induced transformation.

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References

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Authors and Affiliations

  1. Division of Biologics Standards,

    MICHAEL F. BARILE

  2. National Cancer Institute, National Institutes of Health, Bethesda, Maryland

    BRIGID G. LEVENTHAL

Authors
  1. MICHAEL F. BARILE
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  2. BRIGID G. LEVENTHAL
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BARILE, M., LEVENTHAL, B. Possible Mechanism for Mycoplasma Inhibition of Lymphocyte Transformation induced by Phytohaemagglutinin. Nature 219, 751–752 (1968). https://doi.org/10.1038/219751a0

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