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Antilymphocyte Serum produced in Closely Related Species of Baboons with Stored Spleen Cells from Individual Donors

Abstract

THE heterologous antisera to lymphocytes (ALS) have been produced in a number of species, but nobody except Balner1 seems to have used non-human primates to produce them. Most investigators seem to have used freshly prepared cells from different donors at each inoculation. We have immunized gelada baboons with stored spleen cell suspensions of individual cynocephalus baboons. These baboons represent closely related, but different, species.

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References

  1. Balner, H., in Antilymphocytic Serum (edit. by Wolstenholme, G. E. W., and O'Connor, M.), 85 (Little, Brown and Company, Boston, 1967).

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  2. Rowe, A. W., Fed. Proc., 22, 170 (1963).

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  3. Engelfriet, C. P., thesis, Amsterdam (1966).

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NAKAMURA, H., GOLDSMITH, E. & ROWE, A. Antilymphocyte Serum produced in Closely Related Species of Baboons with Stored Spleen Cells from Individual Donors. Nature 219, 294–295 (1968). https://doi.org/10.1038/219294a0

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  • DOI: https://doi.org/10.1038/219294a0

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