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Influenza Antibody in Human Respiratory Secretions after Subcutaneous or Respiratory Immunization with Inactivated Virus

Abstract

STUDIES with human volunteers have shown that experimental infection with influenza virus is a better stimulus of antibody in respiratory secretions than is subcutaneous immunization with inactivated vaccine, although both procedures result in the production of similar concentrations of serum antibody1,2. The work reported here was undertaken to determine if administration of inactivated virus vaccine through the respiratory tract provokes a similar antibody response in respiratory secretions.

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WALDMAN, R., KASEL, J., FULK, R. et al. Influenza Antibody in Human Respiratory Secretions after Subcutaneous or Respiratory Immunization with Inactivated Virus. Nature 218, 594–595 (1968). https://doi.org/10.1038/218594a0

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