Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Antibacterial Nature of Prostatic Fluid

Abstract

Human and canine prostatic fluid is bactericidal for a number of Gram negative and Gram positive bacteria. The fraction responsible for this effect is heat stable, of low molecular weight and is inactivated by normal blood serum. This antimicrobial activity may help to explain why men are less susceptible to infections of the urinary tract than are women.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Dunn, B. L., and Stamey, T. A., J. Urol., 97, 505 (1967).

    Article  CAS  Google Scholar 

  2. Bessey, O. A., Lowry, P., and Brock, M. J., J. Biol. Chem., 164, 321 (1946).

    CAS  PubMed  Google Scholar 

  3. Litwack, G., Proc. Soc. Exp. Biol. and Med., 89, 401 (1955).

    Article  CAS  Google Scholar 

  4. Rosenkrantz, H., and Kirdani, E. S., Cancer Chem. Rep., 15, 9 (1961).

    CAS  Google Scholar 

  5. Goss, W. A., Deitz, W. H., and Cook, T. M., J. Bact., 88, 1112 (1964).

    Article  CAS  Google Scholar 

  6. Newton, B. A., Bacteriol. Rev., 20, 14 (1956).

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Rozansky, R., Bachrach, U., and Grossowicz, N., J. Gen. Microbiol., 10, 11 (1954).

    Article  CAS  Google Scholar 

  8. Rozansky, R., Gurevitch, J., Brezezinsky, A., and Eckerling, B., J. Lab. Clin. Med., 34, 1526 (1949).

    Google Scholar 

  9. Bachrach, U., and Persky, S., J. Gen. Microbiol., 37, 195 (1964).

    Article  CAS  Google Scholar 

  10. Razin, S., and Rozansky, R., Arch. Biochem. Biophys., 81, 36 (1959).

    Article  CAS  Google Scholar 

  11. Gurevitch, J., Rozansky, R., Weber, D., Brezezinsky, A., and Eckerling, B., J. Clin. Pathol., 4, 360 (1951).

    Article  CAS  Google Scholar 

  12. Stamey, T. A., Govan, D. E., and Palmer, J. M., Medicine, 44, 1 (1965).

    Article  CAS  Google Scholar 

  13. Gupta, S. N., Perkash, I., Agarwal, S. C., and Anand, S. S., Investigative Urol., 5, 219 (1967).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

STAMEY, T., FAIR, W., TIMOTHY, M. et al. Antibacterial Nature of Prostatic Fluid. Nature 218, 444–447 (1968). https://doi.org/10.1038/218444a0

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/218444a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing