Abstract
CELLS from a thymus graft are capable of proliferating in response to certain antigenic stimuli but are apparently incapable of producing antibody1, and it has been suggested that these cells, here referred to as reactor cells, have an important role in initiating immune responses2. In a study of this role we posed the question of whether they would continue to respond after heavy doses of antigen.
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References
Davies, A. J. S., Leuchars, E., Wallis, V., Marchant, R., and Elliott, E. V., Transplantation, 5, 222 (1967).
Davies, A. J. S., Leuchars, E., Wallis, V., and Koller, P. C., Transplantation, 4, 438 (1966).
Leuchars, E., Cross, A. M., and Dukor, P., Transplantation, 3, 28 (1965).
Ford, C. E., in Tissue Grafting and Radiation by Micklem, H. S., and Loutit, J. F., 197 (Academic Press, New York and London, 1966).
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GERSHON, R., WALLIS, V., DAVIES, A. et al. Inactivation of Thymus Cells after Multiple Injections of Antigen. Nature 218, 380–381 (1968). https://doi.org/10.1038/218380a0
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DOI: https://doi.org/10.1038/218380a0
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