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New Immunochemical System for Study of Intracellular Host–Parasite Relationships

Abstract

SERUM proteins are often altered when an animal is infected by an intracellular parasite, but do the soluble proteins of the parasitized cell itself change ? This question and others involving intracellular host–parasite relationships were studied using two antigenically different cell lines grown in a chemically defined medium free of antigenic molecules and antibiotics1. In these cloned lines, antigenic differences resulting from the same parasite infection were compared.

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References

  1. Evans, V. J., Bryant, J. C., Kerr, H. A., and Shilling, E. L., Exp. Cell. Res., 38, 439 (1964).

    Article  Google Scholar 

  2. Damian, R. T., Amer. Naturalist, 98, 129 (1964).

    Article  Google Scholar 

  3. Hoagland, C. L., Ward, S. M., Smadel, J. E., and Rivers, T. M., J. Exp. Med., 76, 163 (1942).

    Article  CAS  Google Scholar 

  4. Smith, D. B., dissert., Univ. California, Los Angeles (1967).

  5. Smith, D. B., Anal. Biochem. (in the press).

  6. Allison, A. C., and Humphrey, J. H., Immunology, 3, 95 (1960).

    CAS  PubMed  PubMed Central  Google Scholar 

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SMITH, D. New Immunochemical System for Study of Intracellular Host–Parasite Relationships. Nature 218, 287–288 (1968). https://doi.org/10.1038/218287a0

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  • DOI: https://doi.org/10.1038/218287a0

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