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Aureolic Acid Group of Anti-tumour Antibiotics

Nature volume 218, pages 193–194 (1968)Cite this article

Abstract

SINCE 1953 several antibiotics of similar biological and physico-chemical properties have been described. These are aureolic acid1, aburamycin2, LA-7017 (ref. 3), M5-18903 (ref. 4), chromomycin5, antibiotic 2410 (ref. 6), NSC A-649 (ref. 7), olivomycin8, mithramycin9 and antibiotics 232, 3014, 7193, 11296 (ref. 10) and SK-229 (ref. 11). Two members of this group, olivomycin and chromomycin, were subjected to extensive chemical research which resulted in the isolation and structural elucidation of their components, olivomycins A, B, C, D (ref. 12) and chromomycins A2, A3, A4 (ref. 13). The other members of the group, however, have been only scantily investigated.

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Authors and Affiliations

  1. Institute for Chemistry of Natural Products, USSR Academy of Sciences, Moscow

    Yu. A. BERLIN, O. A. KISELEVA, M. N. KOLOSOV, M. M. SHEMYAKIN, V. S. SOIFER, I. V. VASINA & I. V. YARTSEVA

  2. All-Union Institute of Antibiotics Research, Moscow

    V. D. KUZNETSOV

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  1. Yu. A. BERLIN
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  2. O. A. KISELEVA
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  3. M. N. KOLOSOV
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  4. M. M. SHEMYAKIN
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  6. I. V. VASINA
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  7. I. V. YARTSEVA
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  8. V. D. KUZNETSOV
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BERLIN, Y., KISELEVA, O., KOLOSOV, M. et al. Aureolic Acid Group of Anti-tumour Antibiotics. Nature 218, 193–194 (1968). https://doi.org/10.1038/218193a0

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