Abstract
RNA polymerase activity has been observed in isolated mitochondria of Saccharomyces cerevisiae. Increase in this activity precedes that of other respiratory enzymes, and may be of functional significance in mitochondriogenesis.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Tewari, K. K., Jayaraman, J., and Mahler, H. R., Biochem. Biophys. Res. Commun., 21, 141 (1965); Tewari, K. K., Voetsch, W., Mahler, H. R., and Mackler, B., J. Mol. Biol., 20, 453 (1966).
Corneo, G., Moore, C., Sanadi, D. R., Grossman, L. I., and Marmur, J., Science, 151, 697 (1966).
Moustacchi, and Williamson, H., Biochem. Biophys. Res. Commun., 23, 56 (1966).
Mounolou, J. C., Jakob, H., and Slonimski, P. P., Biochem. Biophys. Res. Commun., 24, 218 (1966).
Avers, C. J., Proc. US Nat. Acad. Sci., 58, 620 (1967).
Sinclair, J. H., Stevens, B. J., Sanghavi, P., and Rabinowitz, M., Science, 156, 1234 (1967).
Luck, D. J. L., and Reich, E. P., Proc. US Nat. Acad. Sci., 52, 831 (1964).
Borst, P., Kroon, A. M., and Ruttenberg, G. J. C. M., Genetic Elements, Properties and Function; Symposium Third Meeting FEBS (edit. by Shugar, D.), 81 (Academic Press, New York, 1967).
Granick, S., and Gibor, A., in Progress in Nucleic Acid Research and Molecular Biology (edit. by Davidson, J. N., and Cohn, W. E.), 6, 143 (1967).
Roodyn, D. B., and Wilkie, D., The Biogenesis of Mitochondria (Methuen Co., London, 1968).
Wintersberger, E., in Regulation of Metabolic Processes in Mitochondria (edit. by Tager, J. M., Papa, S., Quagliarello, E., and Slater, E. C.), 439 (Elsevier, Amsterdam, London, New York, 1966).
Rogers, R. J., Preston, B. N., Titchener, E. B., and Linnane, A. W., Biochem. Biophys. Res. Commun., 27, 405 (1967).
Leon, S., and Mahler, H. R., Arch. Biochem. Biophys. (in the press).
Rifkin, M. R., Wood, D. D., and Luck, D. J. L., Proc. US Nat. Acad. Sci., 58, 1025 (1967).
Dure, L. S., Epler, J. L., and Barnett, W. E., Proc. US Nat. Acad. Sci., 58, 1883 (1967).
Kuntzel, H., and Noll, H., Nature, 215, 1340 (1967).
Barnett, W. E., and Brown, D. H., Proc. US Nat. Acad. Sci., 57, 452 (1967).
Kalf, G. F., Biochemistry, 3, 1702 (1964).
Neubert, D., and Helge, H., Biochem. Biophys. Res. Commun., 18, 600 (1965).
Tewari, K. K., Jayaraman, J., and Mahler, H. R., in Aspects of Yeast Metabolism, Guinness Symposium, Dublin, 1965 (edit. by Mills, A. K.), 247 (Blackwell, Oxford, 1967).
Suyama, Y., and Eyer, J., J. Biol. Chem., 243, 320 (1968).
Ephrussi, B., Slonimski, P. P., Yotsuyanagi, Y., and Tavlitzki, J., C.R. Lab. Carlsberg Ser. Physiol. 26, 87 (1956).
Jayaraman, J., Cotman, C., Mahler, H. R., and Sharp, C., Arch. Biochem. Biophys., 116, 224 (1966).
Reviewed by Elson, D., Ann. Rev. Biochem., 34, 449 (1965).
So, A. G., Davie, E. W., Epstein, R., and Tissierès, A., Proc. US Nat. Acad. Sci., 58, 1739 (1967).
Widnell, C. C., and Tata, J. R., Biochim. Biophys. Acta, 87, 478 (1966).
Hurwitz, J., Furth, J. J., Malamy, M., and Alexander, M., Proc. US Nat. Acad. Sci., 48, 1222 (1962).
Waring, M. J., Symp. Soc. Gen. Microbiol., 16, 237 (1966).
Maitra, U., Nakata, Y., and Hurwitz, J., J. Biol. Chem., 242, 4908 (1967).
Reich, E., and Goldberg, I. H., in Prog. Nucleic Acid Res. and Mol. Biol., 3, 184 (1964).
Parenti, F., and Marguiles, M., Fed. Proc., 26, 1102 (1967).
Holley, R. W., Madison, J. T., and Zamir, A., Biochem. Biophys. Res. Commun., 17, 389 (1964).
Klingenberg, M., and Pfaff, E., in Regulation of Metabolic Processes in Mitochondria (edit. by Tager, J. M., Papa, S., Quagliarello, E., and Slater, E. C.), 180 (Elsevier, Amsterdam, London, New York, 1966).
Caplan, A. I., and Greenawalt, J. W., J. Cell Biol., 16, 15 (1968).
Bachmann, E., Allmann, D. W., and Green, D. E., Arch. Biochem. Biophys., 115, 153 (1965); Allmann, D. W., Bachmann, E., and Green, D. E., ibid., 115, 165 (1966).
Canellakis, E. S., Biochim. Biophys. Acta, 23, 217 (1957).
Sandell, S., Löw, H., and Decken, A. v. d., Biochem. J., 104, 67 (1967) vs Beattie, D. S., Basford, R. E., and Koritz, S. B., J. Biol. Chem., 242, 3366 (1967), and references cited therein.
Neubert, D., Helge, H., and Merker, H. J., Biochem. Z., 343, 44 (1965).
Slonimski, P. P., Symp. Soc. Gen. Microbiol., 3, 76 (1953) and earlier references cited therein.
Ephrussi, B., Nucleo-cytoplasmic Relations in Microorganisms (Clarendon Press, Oxford, 1953).
Roodyn, D. B., and Wilkie, D., The Biogenesis of Mitochondria, 85 (Methuen Co., London, 1968).
Witt, I., Kronau, R., and Holzer, H., Biochim. Biophys. Acta, 118, 522 (1966).
Ferguson, jun., J. J., Boll, M., and Holzer, H., Europ. J. Biochem., 1, 21 (1967).
Utter, M. F., Duell, E. A., and Bernofsky, C., in Aspects of Yeast Metabolism, Guinness Symposium, Dublin, 1965 (edit. by Mills, A. K.), 197 (Blackwell, Oxford, 1967).
Duntze, W., Neumann, D., and Holzer, H., European J. Biochem. 3, 326 (1968).
Fukuhara, H., Biochim. Biophys. Acta, 134, 143 (1967).
Fukuhara, H., Proc. US Nat. Acad. Sci., 58, 1065 (1967).
Bollum, J. Biol. Chem., 234, 2733 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SOUTH, D., MAHLER, H. RNA Synthesis in Yeast Mitochondria: a Derepressible Activity. Nature 218, 1226–1232 (1968). https://doi.org/10.1038/2181226a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2181226a0
This article is cited by
-
On the repression of mitochondrial dna transcription by fructose 1.6-diphosphate and its derepression by cyclic adenosine 3′,5′-monophosphate
Molecular and Cellular Biochemistry (1974)
-
Genetics of resistance to ethidium bromide in the petite-negative yeast Hansenula wingei
Molecular and General Genetics MGG (1973)
-
Mitochondria and chloroplasts as descendants of prokaryotes
Biochemical Genetics (1972)
-
Influence of ethidium bromide on respiration in Schizosaccharomyces pombe
Molecular and General Genetics MGG (1971)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.