New Enzymatic Route for the Inactivation of Angiotensin

Abstract

Experiments show that swine kidney and human urine contain a new angiotensinase that breaks the prolylphenylalanine bond In various peptides. The product of this enzymatic hydrolysis—the N-terminal heptapeptide sequence of angiotensin—is biologically inactive.

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YANG, H., ERDÖS, E. & CHIANG, T. New Enzymatic Route for the Inactivation of Angiotensin. Nature 218, 1224–1226 (1968) doi:10.1038/2181224a0

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