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Amino-acid Composition of Soluble and Membranous Lipoproteins

Abstract

DURING a study of the amino-acid composition of 140 proteins, wre noted that the compositions of soluble and membranous lipoproteins differ. The observed differences are statistically significant and are related to the different environments to which the protein moieties are exposed. These data have not been collated elsewhere, and they are presented here in the hope that theoretical and experimental studies of lipoprotein structure will be facilitated. Preliminary reports have already been made1–3.

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References

  1. Hatch, F. T., Nature, 206, 777 (1965).

    Article  ADS  CAS  Google Scholar 

  2. Hatch, F. T., and Bruce, A. L., Abs. Seventh Internat. Cong. Biochem., Tokyo, 4, Abstr. A-l12 (1967).

  3. Hatch, F. T., Bruce, A. L., and Harrison, F. L., Fed. Proc., 27, 285 (1968).

    Google Scholar 

  4. Shore, V. G., and Shore, B., Biochemistry, 6, 1962 (1967).

    Article  CAS  Google Scholar 

  5. Margolis, S., and Langdon, R. G., J. Biol. Chem., 241, 469 (1966).

    CAS  Google Scholar 

  6. Levy, R. S., Lynch, A. C., McGee, E. D., and Mehl, J. W., J. Lipid Res., 8, 463 (1967).

    PubMed  CAS  Google Scholar 

  7. Cook, W. H., Burley, R. W., Martin, W. G., and Hopkins, J. W., Biochim. Biophys. Acta, 60, 98 (1962).

    Article  CAS  Google Scholar 

  8. Wathen, J. D., and Levy, R. S., Biochemistry, 5, 1099 (1966).

    Article  CAS  Google Scholar 

  9. Hatch, F. T., Aso, Y., Hagopian, L. M., and Rubenstein, J. J., J. Biol. Chem., 241, 1655 (1966).

    PubMed  CAS  Google Scholar 

  10. Criddle, R. S., Bock, R. M., Green, D. E., and Tisdale, H., Biochemistry, 1, 827 (1962).

    Article  CAS  Google Scholar 

  11. Tenenbaum, D., and Folch-Pi, J., Biochim. Biophys. Acta, 115, 141 (1966).

    Article  CAS  Google Scholar 

  12. Schichi, H., Sugimura, Y., and Funahashi, S., Biochim. Biophys. Acta, 97, 483 (1964).

    Article  Google Scholar 

  13. Manganiello, V. C., and Phillips, A. H., J. Biol. Chem., 240, 3951 (1965).

    PubMed  CAS  Google Scholar 

  14. Morgan, T. E., and Hanahan, D. J., Biochemistry, 5, 1050 (1966).

    Article  CAS  Google Scholar 

  15. Burkhard, R. K., and Klaassen, D. H., Comp. Biochem. Physiol., 18, 231 (1966).

    Article  CAS  Google Scholar 

  16. Criddle, R. S., in Biochemistry of Chloroplasts (edit. by Goodwin, T. W.) 1, 203 (Academic Press, New York, 1966).

    Google Scholar 

  17. Bailey, J. L., Thornber, J. P., and Whyborn, A. G., in Biochemistry of Chloroplasts (edit. by Goodwin, T. W.), 1, 243 (Academic Press, New, York, 1966).

    Google Scholar 

  18. Danielli, J. F., and Davson, H. A., J. Cell. Comp. Physiol., 5, 495 (1935).

    Article  CAS  Google Scholar 

  19. O'Brien, J. S., J. Theoret. Biol., 15, 307 (1967).

    Article  CAS  Google Scholar 

  20. Chapman, D., Science Journal, 4, 55 (1968).

    Google Scholar 

  21. Lenard, J., and Singer, S. J., Science, 159, 738 (1968).

    Article  ADS  CAS  Google Scholar 

Download references

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HATCH, F., BRUCE, A. Amino-acid Composition of Soluble and Membranous Lipoproteins. Nature 218, 1166–1168 (1968). https://doi.org/10.1038/2181166a0

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