Abstract
L-Asparaginase catalyses the hydrolysis of L-asparagine to L-aspartic acid and ammonia. Interest in this enzyme has been stimulated by the discovery that it inhibits the growth of several experimental tumours1–3. L-Asparaginase is being used clinically to treat various leukaemias, lymphomas arid melanomas4, and it was recently shown to inhibit the early mitosis of regenerating livers in rats5. This communication concerns the effects of L-asparaginase on another rapidly growing tissue, the rabbit embryo.
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References
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ADAMSON, R., FABRO, S. Embryotoxic Effect of L-Asparaginase. Nature 218, 1164–1165 (1968). https://doi.org/10.1038/2181164a0
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DOI: https://doi.org/10.1038/2181164a0
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