Abstract
EXTERNALLY applied pressures have been shown to inhibit cell division in vitro1–6 and to inhibit the growth of transplanted and spontaneous solid tumours in mice7,8. It has been proposed that animal cells have internal pressure gradients which are susceptible to external pressures9. The experiments reported in this paper were designed to study the effects of a range of pressures at varying O2 tensions on the growth of a transplanted mouse leukaemia.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Landau, J., and McAlear, J., Cancer Res., 21, 812 (1961).
Landau, J., Exp. Cell Res., 23, 538 (1961).
Landau, J., Zimmerman, A., and Marsland, D., J. Cell Comp. Physiol., 44, 211 (1954).
Marsland, D., Intern. Rev. Cytol., 5, 199 (1956).
Pease, D., Biol. Bull., 91, 145 (1946).
Zimmerman, A., and Silberman, L., Exp. Cell Res., 38, 454 (1965).
Arkin, A., and Sugiara, K., Cancer Res., 10, 272 (1950).
Marsh, M., Amer. J. Cancer., 15, 2252 (1931).
Doerner, jun., K., J. Theoret. Biol., 14, 284 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DOERNER, K., SANFORD, S. & LIEBELT, R. Pressure Effects on Survival of Mice with Transplantable Leukaemia. Nature 218, 98–99 (1968). https://doi.org/10.1038/218098a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/218098a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
