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In vitro Detection of Immunosuppressive Activity of Anti-lymphocyte Sera

Nature volume 217, pages 658–659 (1968)Cite this article

Abstract

THE problem of in vitro evaluation of anti-lymphocyte sera (ALS) has not yet been solved. The tests used, such as leuco-agglutination, cytotoxicity and lymphocyte stimulation in culture, do not detect small amounts of anti-lymphocyte antibodies and, furthermore, the results of these tests are not regularly correlated with graft survival time1,2. We propose a new in vitro test, based on inhibition of an active function of the lymphocytes.

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Authors and Affiliations

  1. Tissue Immunology Laboratory, Nephrology Clinic, Hôpital Necker, University of Paris,

    J. F. BACH & B. ANTOINE

Authors
  1. J. F. BACH
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  2. B. ANTOINE
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BACH, J., ANTOINE, B. In vitro Detection of Immunosuppressive Activity of Anti-lymphocyte Sera. Nature 217, 658–659 (1968). https://doi.org/10.1038/217658a0

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