Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Effect of Phenylhydrazine and Hydrolysed Glucose Cycloacetoacetate on Adenosinetriphosphatase Activity in Liver Mitochondria


ALTHOUGH freshly prepared liver mitochondria are unable to hydrolyse ATP at a perceptible rate1, damaging liver mitochondria is known to bring about ATP hydrolysis2. Deleterious effects of phenylhydrazine on liver have also been reported3,4.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Kielley, W. W., and Kielley, R. K., J. Biol. Chem., 200, 213 (1953).

    CAS  PubMed  Google Scholar 

  2. 2

    Myers, D. K., and Slater, E. C., Nature, 179, 363 (1957).

    ADS  CAS  Article  Google Scholar 

  3. 3

    Chanutin, A., Lentz, E. A., and Ludewig, S., Amer. J. Physiol., 173, 474 (1953).

    CAS  Article  Google Scholar 

  4. 4

    Damodaran, M., and Vijayraghavan, P. K., Curr. Sci., 12, 115 (1943).

    CAS  Google Scholar 

  5. 5

    Nath, M. C., and Prasannan, K. G., Biochem. J., 73, 729 (1959).

    CAS  Article  Google Scholar 

  6. 6

    Brahmankar, D. M., Meghal, S. K., and Nath, M. C., Ind. J. Biochem., 1, 167 (1964).

    Google Scholar 

  7. 7

    Krishnamurthi, V., Nayudu, S. G., and Nath, M. C., Proc. Soc. Exp. Biol. and Med., 117, 861 (1964).

    CAS  Article  Google Scholar 

  8. 8

    Nath, N., Yawalkar, V. D., and Nath, M. C., Nature, 208, 1001 (1965).

    ADS  CAS  Article  Google Scholar 

  9. 9

    Artizzu, M., Baccino, F. M., and Dianzani, M. U., Biochim. Biophys. Acta, 78, 1 (1963).

    CAS  Article  Google Scholar 

  10. 10

    West, E. S., J. Biol. Chem., 74, 561 (1927).

    CAS  Google Scholar 

  11. 11

    Nath, M. C., Chitale, B. P., and Belavady, B., Nature, 170, 545 (1952).

    ADS  CAS  Article  Google Scholar 

  12. 12

    Nath, M. C., and Nath, N., Ind. J. Med. Res., 53, 1010 (1965).

    CAS  Google Scholar 

  13. 13

    Schneider, W. C., and Hogeboom, G. H., J. Biol. Chem., 183, 123 (1950).

    CAS  Google Scholar 

  14. 14

    Fiske, C. H., and Subba Row, Y., J. Biol. Chem., 66, 375 (1925).

    CAS  Google Scholar 

Download references

Author information



Rights and permissions

Reprints and Permissions

About this article

Cite this article

NATH, M., REDDI, T. & NATH, N. Effect of Phenylhydrazine and Hydrolysed Glucose Cycloacetoacetate on Adenosinetriphosphatase Activity in Liver Mitochondria. Nature 217, 552–553 (1968).

Download citation


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing