Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Effect of Bromide Ions on Junctional Transmission

Abstract

THE efficacy of bromides as hypnotics or sedatives has long been recognized, but their mode of action is unknown. Many drugs which affect the central nervous system, alcohols and barbiturates, for example, have been shown to influence synaptic activity1–3 and it seemed likely that bromides might act similarly. The effect of bromide ions on transmission at the neuromuscular junction has therefore been investigated.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Gage, P. W., J. Pharmacol., 150, 236 (1966).

    Google Scholar 

  2. 2

    Thesleff, S., Acta Physiol. Scand., 37, 335 (1956).

    CAS  Article  Google Scholar 

  3. 3

    Løyning, Y., thesis, Australian Nat. Univ. (1966).

  4. 4

    Harris, E. J., J. Physiol., 141, 351 (1958).

    CAS  Article  Google Scholar 

  5. 5

    Hutter, O. F., and Padsha, S. M., J. Physiol., 146, 117 (1959).

    CAS  Article  Google Scholar 

  6. 6

    Del Castillo, J., and Katz, B., J. Physiol., 124, 586 (1954).

    CAS  Article  Google Scholar 

  7. 7

    Liley, A. W., J. Physiol., 134, 427 (1956).

    CAS  Article  Google Scholar 

  8. 8

    Gage, P. W., and Quastel, D. M. J., J. Physiol., 185, 95 (1966).

    CAS  Article  Google Scholar 

  9. 9

    Hodgkin, A. L., and Horowicz, P., J. Physiol., 153, 404 (1960).

    CAS  Article  Google Scholar 

  10. 10

    Hubbard, J. I., and Willis, W. D., Nature, 193, 1294 (1962).

    ADS  CAS  Article  Google Scholar 

  11. 11

    Bloedel, J., Gage, P. W., Llinás, R., and Quastel, D. M. J., Nature, 212, 49 (1966).

    ADS  CAS  Article  Google Scholar 

  12. 12

    Del Castillo, J., and Katz, B., J. Physiol., 124, 560 (1954).

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

MUCHNIK, S., GAGE, P. Effect of Bromide Ions on Junctional Transmission. Nature 217, 373–374 (1968). https://doi.org/10.1038/217373a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing