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DNA Restriction Enzyme from E. coli

Abstract

An endonuclease which degrades foreign DNA has been isolated. The enzyme requires S-adenosylmethionine, ATP and Mg++.

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References

  1. Luria, S. E., Cold Spring Harbor Symp. Quant. Biol., 18, 237 (1953).

    Article  CAS  Google Scholar 

  2. Bertani, G., and Weigle, J. J., J. Bacteriol., 65, 113 (1953).

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Arber, W., Ann. Rev. Microbiol., 365 (1965).

  4. Colson, C., Glover, S. W., Symonds, N., and Stacey, K. A., Genetics, 52, 1043 (1965).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Wood, W. B., J. Mol. Biol., 16, 118 (1966).

    Article  CAS  Google Scholar 

  6. Eskridge, R. W., Weingeld, H., and Paigen, K., J. Bacteriol., 93, 835 (1967).

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Kerszman, G., Glover, S. W., and Avonovitch, J., J. Gen. Virol., 1, 333 (1967).

    Article  CAS  Google Scholar 

  8. Arber, W., J. Mol. Biol., 11, 247 (1965).

    Article  CAS  Google Scholar 

  9. Klein, A., and Sauerbier, W., Biochem. Biophys. Res. Commun., 18, 440 (1965).

    Article  CAS  Google Scholar 

  10. Appleyard, R. K., Genetics, 39, 440 (1954).

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Okada, T., Homma, J., and Sonohara, H., J. Bact., 84, 602 (1962).

    CAS  PubMed  Google Scholar 

  12. Durwald, H., and Hoffman-Berling, H., J. Mol. Biol. (in the press).

  13. Meselson, M., J. Mol. Biol., 9, 734 (1964).

    Article  CAS  Google Scholar 

  14. Kaiser, A. D., Virology, 3, 42 (1957).

    Article  CAS  Google Scholar 

  15. Hradecna, Z., and Szybalski, W., Virology, 32, 633 (1967).

    Article  CAS  Google Scholar 

  16. Kaiser, A. D., and Hogness, D. S., J. Mol. Biol., 2, 392 (1960).

    Article  CAS  Google Scholar 

  17. Studier, F. W., J. Mol. Biol., 11, 373 (1965).

    Article  CAS  Google Scholar 

  18. Bode, V. C., and Kaiser, A. D., J. Mol. Biol., 14, 399 (1965).

    Article  CAS  Google Scholar 

  19. Heinemann, S., dissert., Harvard Univ. (1967).

  20. Takano, T., Watanabe, T., and Fukasawa, T., Biochem. Biophy. Res. Commun., 25, 192 (1966).

    Article  CAS  Google Scholar 

  21. Arber, W., Hattman, S., and Dussoix, D., Virology, 21, 30 (1963).

    Article  CAS  Google Scholar 

  22. Lederberg, S., and Meselson, M., J. Mol. Biol., 8, 623 (1964).

    Article  CAS  Google Scholar 

  23. Lehman, I. R., Ann. Rev. Biochem., 36, 645 (1967).

    Article  CAS  Google Scholar 

  24. Boyer, H., J. Bact., 88, 1652 (1964).

    CAS  PubMed  Google Scholar 

  25. Lark, C., J. Mol. Biol., 31, 401 (1968).

    Article  CAS  Google Scholar 

Download references

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MESELSON, M., YUAN, R. DNA Restriction Enzyme from E. coli. Nature 217, 1110–1114 (1968). https://doi.org/10.1038/2171110a0

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