Sex Chromosome Abnormalities


DURING the past decade several surveys have related the incidence of sex chromosome abnormalities among the general population with that among mentally deficient patients in hospital1–3. In 1963 Wegmann arid Smith4 carried out a buccal smear survey among a male population composed of juvenile delinquents and felons. They found the incidence of positive for sex chromatin lower (1 : 658) than in the neonatal population (1 : 377) and suggested that the XXY aberration does not contribute disproportionately to juvenile delinquency or felonious behaviour. Nevertheless, evidence is beginning to suggest that genetic factors influence criminal behaviour. Jacobs et al.5 have called attention to the criminal behaviour of males with the XYY sex chromosome complement.

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  1. 1

    Moore, K. L., Lancet, ii, 217 (1959).

  2. 2

    MacLean, N., Harnden, D. G., and Court Brown, W. M., Lancet, ii, 406 (1961).

  3. 3

    MacLean, N., Mitchell, J. M., Harnden, D. G., Williams, J., Jacobs, P. A., Buckton, E. K., Baikie, A. G., Court Brown, W. M., McBride, J. A., Strong, J. A., Close, H. G., and Jones, D. C., Lancet, i, 293 (1962).

  4. 4

    Wegmann, T. G., and Smith, D. W., Lancet, i, 274 (1963).

  5. 5

    Jacobs, P. A., Brunton, M., Melville, M. M., Brittain, R. P., and McClemont, W. F., Nature, 208, 1351 (1965).

  6. 6

    Forssman, H., and Hambert, G., Lancet, i, 1327 (1963).

  7. 7

    Welch, J. P., Borgaonkar, D. S., and Herr, H. M., Nature, 214, 500 (1967).

  8. 8

    Hope, K., Philip, A. E., and Loughran, J. M., Brit. J. Psychiat., 113, 495 (1967).

  9. 9

    Hauschka, T. S., Hasson, J. E., Goldstein, M. N., Koepf, G. F., and Sandberg, A. A., Amer. J. Human Genet., 14, 22 (1962).

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GOODMAN, R., SMITH, W. & MIGEON, C. Sex Chromosome Abnormalities. Nature 216, 942–943 (1967).

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