Abstract
Prostaglandins are released into the splenic venous blood when the spleen contracts. Whatever the significance of this release, the liver and lungs provide an efficient protective mechanism to remove almost all the prostaglandin before it reaches the arterial circulation.
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FERREIRA, S., VANE, J. Prostaglandins: Their Disappearance from and Release into the Circulation. Nature 216, 868–873 (1967). https://doi.org/10.1038/216868a0
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DOI: https://doi.org/10.1038/216868a0
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