Rare Pseudoallelic Crossover between Two Phenotypically Identical Alleles at a Restricted Sublocus of Dumpy in Drosophila melanogaster

Abstract

THE dumpy locus has been extensively mapped1–4. Many of the sites within the dumpy gene have phenotypic specificity ; that is, mutants of similar phenotypes map at the same restricted part of the region. A series of mutants which show an ov phenotype (oblique wings and thoracic vortices) were mapped to the right of lv1 and to the left of v2 (ref. 4). The ov mutants are viable as homozygotes and in combination with each other, except for ovh, which is a facultative lethal in the homozygote but which is viable with the other ov alleles. The ovh allele also shows a more extreme phenotype, and it is distinguishable in combination with other ov mutants by a more extreme phenotype. A crossover between ov1 and ovh was obtained by Southin5. The work reported here was carried out using other ov alleles of indistinguishable phenotype (ov1 and ov52b) in an attempt to establish critically the fine structure of the dumpy locus by obtaining crossovers between those alleles.

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References

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    Carlson, E. A., Genetics, 44, 347 (1959).

  2. 2

    Carlson, E. A., and Southin, J. L., Genetics, 47, 1017 (1962).

  3. 3

    Grace, D., thesis, Univ. California, Los Angeles (1966).

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    Sederoff, R., and Carlson, E. A., Drosophila Information Service, 35, 75 (1961).

  5. 5

    Southin, J. L., cited in Carlson, E. A., The Gene: A Critical History (W. B. Saunders Company, Philadelphia, Pennsylvania, 1966).

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    Stevens, W. L., J. Genet., 43, 301 (1942).

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SEDEROFF, R. Rare Pseudoallelic Crossover between Two Phenotypically Identical Alleles at a Restricted Sublocus of Dumpy in Drosophila melanogaster. Nature 216, 1348–1349 (1967). https://doi.org/10.1038/2161348b0

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