Bioassay of Captan by Zebrafish Larvae


CAPTAN (N-trichloromethylthio-4-cyclohexene-1,2-dicarboxyimide) is an agricultural fungicide of low mammalian toxicity, and its residues*; in agricultural products are considered to offer less risk than most pesticides. A recent report1 draws attention to the mutagenic and teratogenic properties of captan, which has been observed to increase the mutation rate in bacteria (Escherichia coli), to inhibit mitotic division in the cell cultures and to induce physical abnormalities in chicks treated in the embryonic stage.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Legator, M., and Verrett, J., New York Academy of Sciences, Conference on Biological Effects of Pesticides in Mammalian Systems”, abstract of paper 6, 17 (1967).

  2. 2

    Richmond, D. V., and Somers, E., Ann. Appl. Biol., 50, 33 (1962).

Download references

Author information



Rights and permissions

Reprints and Permissions

About this article

Cite this article

ABEDI, Z., MCKINLEY, W. Bioassay of Captan by Zebrafish Larvae. Nature 216, 1321–1322 (1967).

Download citation

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.