Inhibition of Multiplication of Foot and Mouth Disease Virus in Adult Mice pretreated with Freund's Complete Adjuvant

Abstract

INCREASED resistance has been reported in certain virus infections after stimulation of the reticulo-endothelial system (RES)1,2. We have observed that, in adult mice pretreated with complete Freund's adjuvant3, the multiplication of foot and mouth disease virus (FMDV) is inhibited4, and we report here the results of further experiments.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Lubke, A., Zentbl. Bakt. Parasitkde., I, 200, 290 (1966).

  2. 2

    Rowson, K. E. K., Mahy, B. W. J., and Salaman, H. H., J. Exp. Med., 122, 983 (1965).

  3. 3

    Freund, J., J. Immunol., 18, 315 (1930).

  4. 4

    Gorhe, D., Aynaud, J. M., and Paraf, A., C.R. Acad. Sci., 264, 2698 (1967).

  5. 5

    Gorhe, D. S., thesis, Univ. Paris (in the press).

  6. 6

    Jullien, P., and De Maeyer, E., Intern. J. Radial. Biol., 11, 567 (1966).

  7. 7

    Jollès, P., Samour, D., and Lederer, E., Arch. Biochem. Biophys., suppl. 1, 283 (1962).

  8. 8

    Baron, S., Adv. Virus Res., 10, 39 (1963).

  9. 9

    Youngner, J. S., and Stinebring, W. R., Nature, 208, 456 (1965).

  10. 10

    Duplan, J. F., Paraf, A., and Moraillon, A. M., Ann. Inst. Pasteur, 106, 828 (1964).

  11. 11

    Houdayer, M., Metzger, J. J., and Paraf, A., Prog. Immunobiol. Standard., 2, 63 (1964).

  12. 12

    Paraf, A., and Moraillon, A. M., C.R. Acad. Sci., 258, 3598 (1964).

  13. 13

    Fruitstone, M. J., Michaels, B. S., Rudloff, D. A. C., and Sigel, M. M., Proc. Soc. Exp. Biol. and Med., 122, 1008 (1966).

  14. 14

    Gresser, I., Proc. Soc. Exp. Biol. and Med., 108, 799 (1961).

  15. 15

    Glasgow, L. A., J. Bact., 91, 2185 (1966).

  16. 16

    Kono, Y., and Ho, N., Virology, 25, 162 (1965).

  17. 17

    Smith, T. J., and Wagner, R. R., J. Exp. Med., 125, 559 (1967).

Download references

Author information

Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

GORHE, D. Inhibition of Multiplication of Foot and Mouth Disease Virus in Adult Mice pretreated with Freund's Complete Adjuvant. Nature 216, 1242–1244 (1967). https://doi.org/10.1038/2161242a0

Download citation

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.