Abstract
THE effects of ovarian hormones on the cell cycle of target tissues have been extensively studied. It has been shown that high doses of oestrogens of exogenous origin can alter the duration of DNA synthesis (S phase) in target tissues when administered alone1,2 or in association with progesterone3.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Peckham, B., Ladinsky, J., and Kiekhofer, W., Amer. J. Obstet. Gynecol., 87, 710 (1963).
Epifanova, O. I., Exp. Cell Res., 42, 562 (1966).
Bresciani, F., Science, 146, 653 (1964).
Galand, P., Rodesch, F., Leroy, F., and Chretien, J., Exp. Cell Res. (in the press).
Maurer, W., Pilgrim, Ch., Wegener, K., Hollweg, S., and Lennartz, J., in Klinik und Forschung (edit. by Fellinger, K., and Höfer, R.), 6, 96 (Urban und Schwarzenberg, Berlin, 1965).
Bresciani, F., Exp. Cell. Res., 38, 13 (1965).
Banerjee, M. R., and Walker, R. J., J. Cell Physiol., 69, 133 (1967).
Trasher, J. D., Clark, F. I., and Clarke, D. R., Exp. Cell. Res., 45, 232 (1967).
Quastler, M., and Sherman, F. G., Exp. Cell Res., 17, 420 (1959).
Bullough, W. S., and Lawrence, E. B., Exp. Cell. Res., 43, 343 (1966).
Pilgrim, Ch., Lang, W., and Maurer, W., Exp. Cell. Res., 17, 420 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GALAND, P., RODESCH, F., LEROY, F. et al. Altered Duration of DNA Synthesis and Cell Cycle in Non-target Tissues of Mice treated with Oestrogen. Nature 216, 1211–1212 (1967). https://doi.org/10.1038/2161211a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/2161211a0
This article is cited by
-
An autoradiographical topological study of the epithelial cell proliferative activity in the ascending colon of the mouse using a modified technique for determining the fraction of labelled mitoses (FLM)
Virchows Archiv B Cell Pathology Including Molecular Pathology (1983)
-
Effect of estrogen on cell proliferation in colonic mucosa of the mouse
Virchows Archiv B Cell Pathology Including Molecular Pathology (1980)
-
Effect of an A′aqueous extract of small intestinal mucosa on the G-2 phase of jejunal proliferative cells in mice
Virchows Archiv B Cell Pathology (1973)
-
Effect of hydrocortisone on duration of periods of mitotic cycle in esophageal epithelium of mice
Bulletin of Experimental Biology and Medicine (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
