THE currently accepted theory of maternal blood flow through the intervillous space of the primate placenta1 is that maternal blood entering through basally situated spiral arterioles spurts up towards the chorionic plate under the influence of the vis a tergo of the maternal arterial pressure, spreads laterally and falls back to drain through basal venous openings. Short circuiting from artery to adjacent vein is believed to be avoided purely by virtue of the arterial pressure. This theory based on. cineangiographic evidence takes no account of the structure of the foetal portion of the placenta. The latter consists of numerous lobules or cotyledons of which the principal fifty to sixty are arranged in the form of hollow centred bush-like structures as seen in corrosion casts of the foetal vasculature2,3. Each lobule arises by a main chorionic stem, and is supplied through a major branch of an umbilical artery. Subsequent branches supply an extensive capillary network within the mass of terminal villi which crowd round the central intralobular space. This lobular pattern can be recognized in histological sections in the form of dense masses of villi orientated round cavities4. Interlobular and subchorial areas show greater separation between the villi.
Subscribe to Journal
Get full journal access for 1 year
only $3.90 per issue
All prices are NET prices.
VAT will be added later in the checkout.
Rent or Buy article
Get time limited or full article access on ReadCube.
All prices are NET prices.
Ramsey, E. M., Amer. J. Obstet. Gynec., 84, 1649 (1962).
Wilkin, P., in The Placenta and Fetal Membranes (edit. by Villee, C. A.), 154 (Williams and Wilkins, Baltimore, 1960).
Crawford, J. M., Amer. J. Obstet. Gynec., 84, 1543 (1962).
Gruenwald, P., Bull. Johns Hopkins Hosp., 119, 172 (1966).
Wigglesworth, J. S., thesis, Univ. Cambridge, 12 (1964).
Reynolds, S. R. M., Amer. J. Obstet. Gynec., 94, 425 (1966).
Freese, U. E., Amer. J. Obstet. Gynec., 94, 354 (1966).
Ramsey, E. M., Martin, C. B., and Donner, M. W., Amer. J. Obstet. Gynec., 98, 419 (1967).
Burchell, R. C., Amer. J. Obstet. Gynec., 98, 303 (1967).
Boyd, J. D., and Hamilton, W. J., J. Obstet. Gynaec. Brit. Cwlth., 74, 161 (1967).
About this article
Cite this article
WIGGLESWORTH, J. Vascular Organization of the Human Placenta. Nature 216, 1120–1121 (1967). https://doi.org/10.1038/2161120a0
Journal of Obstetrics and Gynaecology Research (2011)
Longitudinal Blood Flow in Shared (Arteriovenous Anastomoses) and Non-Shared Cotyledons in Monochorionic Placentae
Determinants of flow along arterio-arterial anastomoses in monochorionic placentae by dynamic computer modelling of chorionic plate vasculature
Prenatal Diagnosis (2006)
Histomorphometric Characterisation of Shared and Non-shared Cotyledonary Villus Territories of Monochorionic Placentae in Relation to Pregnancy Complications