Abstract
THE recent finding of relatively large concentrations of inosine triphosphate (ITP) (44–51 µg of phosphorus/g of haemoglobin) in erythrocytes obtained from two members of a family1 led to a closer investigation of the nucleotide composition of normal erythrocytes. A detailed analysis of several samples of fresh human erythrocytes revealed the presence of small amounts of ITP in an average concentration of 1.8 µg of phosphorus/g of haemoglobin2. From these studies it was concluded that ITP is a normal constituent of human erythrocytes.
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References
Vanderheiden, B. S., Proc. Tenth Cong. Intern. Soc. Blood Transf. Stockholm 1964, 540 (1965).
Vanderheiden, B. S., Biochem. Biophys. Res. Commun., 21, 265 (1965).
Vanderheiden, B. S., Anal. Biochem., 8, 1 (1964).
Vanderheiden, B. S., and Boszormenyi-Nagy, I., Anal. Biochem., 13, 496 (1965).
Vanderheiden, B. S., Anal. Biochem. (in the press).
Lowy, B. A., Williams, M. K., and London, I. M., J. Biol. Chem., 237, 1622 (1962).
Bishop, C., J. Biol. Chem., 235, 3228 (1964).
Klein, W., Hoppe Seyl. Zeit. Physiol. Chem., 338, 168 (1964).
Mager, J., Dvilansky, A., Razin, A., Wind, E., and Izak, G., Israel J. Med. Sci., 2, 297 (1966).
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VANDERHEIDEN, B. Phosphate Esters of Human Erythrocytes: Synthesis of ITP-14C from Inosine-8-14C. Nature 216, 1036–1037 (1967). https://doi.org/10.1038/2161036a0
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DOI: https://doi.org/10.1038/2161036a0
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