Improved Multi-enzyme Analyser


BY a relatively simple adaptation of the Technicon auto-analyser system, it was possible to develop a technique for the automatic assay of groups of enzymes1. The reaction mixture—for example, a tissue homogenate, buffer and any co-factors common to all the enzymes in the group—flows continuously through the analyser. Different substrates are then introduced through the automatic sampler, so that the various enzymes in the homogenate which react with these substrates are assayed in sequence.

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    Roodyn, D. B., Nature, 206, 1226 (1965).

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    Tappel, A. L., and Beck, C., in Autom. Anal. Chem.: Technicon Symposia 1965, 559 (Mediad, Inc., New York, 1966).

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ROODYN, D. Improved Multi-enzyme Analyser. Nature 216, 1033–1036 (1967).

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