Abstract
CONSIDERABLE effort has been expended in the search for a non-toxic substance which will reduce the intestinal absorption of radioactive strontium without interfering with calcium absorption. A compound which approaches these requirements is an extract from brown seaweed known commercially as sodium alginate. It consists of a mixed polymer of L-guluronic and D-mannuronic acids, of which the ratio, referred to as the G/M ratio, depends on the botanical source and the method of extraction.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Skoryna, S. C., Paul, T. M., and Waldron-Edward, D., Canad. Med. Assoc. J., 91, 285 (1964).
Paul, T. M., Waldron-Edward, D., and Skoryna, S. C., Canad. Med. Assoc. J., 91, 553 (1964).
Waldron-Edward, D., Paul, T. M., and Skoryna, S. C., Canad. Med. Assoc. J., 91, 1006 (1964).
Hesp, R., and Ramsbottom, B., Nature, 208, 1341 (1965).
Harrison, G. E., Humphreys, E. R., Sutton, A., and Shepherd, H. Science, 152, 655 (1966).
Harrison, J., McNeill, K. G., and Janiga, A., Canad. Med. Assoc. J., 95, 532 (1966).
Waldron-Edward, D., Paul, T. M., and Skoryna, S. C., Nature, 205, 1117 (1965).
Patrick, G., Carr, T. E. F., and Humphreys, E. R., Intern. J. Radiat. Biol. (in the press).
Hesp, R., and Ramsbottom, B., in Strontium Metabolism, 313 (Academic Press, London, 1967).
Waldron-Edward, D., Skoryna, S. C., and Paul, T. M., in Strontium Metabolism, 329 (Academic Press, London, 1967).
Humphreys, E. R., Carbohydrate Res. (in the press).
Bishop, M., Harrison, G. E., Raymond, W. H. A., and Sutton, A., Intern. J. Radiat. Biol., 2, 125 (1960).
Barnes, D. W. H., Bishop, M., Harrison, G. E., Sutton, A., and Rundo, J., Intern. J. Radiat. Biol. 3, 637 (1961).
Carr, T. E. F., Harrison, G. E., and Sutton, A., Proc. Soc. Exp. Biol., 110, 151 (1962).
Fujita, M., Yabe, A., Ueno, K., Oshino, M., and Okuyama, N., Health Physics, 9, 407 (1963).
Nordin, B. E. C., Smith, D. A., MacGregor, J., and Nisbet, J., Technical Report, No. 32, Second Panel Report, 124, Vienna (International Atomic Energy Agency, 1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SUTTON, A. Reduction of Strontium Absorption in Man by the Addition of Alginate to the Diet. Nature 216, 1005–1007 (1967). https://doi.org/10.1038/2161005a0
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1038/2161005a0
This article is cited by
-
Human biokinetics of strontium—part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration
Radiation and Environmental Biophysics (2006)
-
Retention of137Cs by algal polysaccharides
Journal of Radioanalytical and Nuclear Chemistry Letters (1994)
-
Evaluation of the effects of chelation therapy with time following strontium exposure to mice
Archives of Environmental Contamination and Toxicology (1991)
-
Effect of Alginate on the Absorption of Lead in Man
Nature (1969)
-
Absorption by the Rat of Alginate labelled with Carbon-14
Nature (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.