Abstract
BLOCH1 showed that different nuclei of a tissue react differently when the tissue is stained with a mixture of fast green and eosin. He found that fast green has a higher affinity for histones rich in arginine, and eosin for histones rich in lysine, and that in some cell types cessation or slowing of the synthesis of RNA is associated with acquisition of an eosinophilic histone.
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CLAYPOOL, C., BLOCH, D. Synthesis of Ribonucleic Acid and Histone Change during Spermatogenesis in the Grasshopper Chortophaga viridifasciata. Nature 215, 966–967 (1967). https://doi.org/10.1038/215966a0
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DOI: https://doi.org/10.1038/215966a0
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