Abstract
BISALBUMINAEMIA is a rare inherited condition, with no clinical features, in which the plasma contains two albumins of different electrophoretic mobilities, usually in equal concentrations: the total concentration of albumin is normal. In all the families so far described, one of the albumins has migrated at the same rate as normal albumin; in some families the second albumin has migrated more slowly and in others more rapidly. Some of the reported variations in the characteristics of the two albumins have been discussed by Tárnoky1. The recent finding of homozygotes for the fast variant in two American Indian families has supported the hypothesis that the determinants for the albumins are alleles at a single locus2,3.
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References
Tárnoky, A. L., Proc. Assoc. Clin. Biochem., 4, 12 (1966).
Melartin, L., and Blumberg, B. S., Science, 153, 1664 (1966).
Bell, H. E., Nicholson, S. F., and Thompson, Z. R., Clin. Chim. Acta, 15, 247 (1967).
Earle, D. P., Hutt, M. P., Schmid, K., and Gitlin, D., J. Clin. Invest., 38, 1412 (1959).
Robbins, J. L., Hills, S., Marcus, G. A., and Carlquist, J. H., J. Lab. Clin. Med., 62, 753 (1963).
Grabar, P., in Immunoelectrophoretic Analysis (edit. by Grabar, P., and Burtin, P.) (Elsevier, Amsterdam, 1964).
Gitlin, D., Schmid, K., Earle, D. P., and Givelber, H., J. Clin. Invest., 40, 820 (1961).
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PAYNE, R., DICKINSON, J. Immunochemical Studies on Bisalbuminaemia. Nature 215, 536–537 (1967). https://doi.org/10.1038/215536a0
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DOI: https://doi.org/10.1038/215536a0
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