Formation of Blue Oxidation Product from Psilocybin


Gilmour and O'Brien1 have reported that a blue colour develops when psilocybin (4-phosphoryl-N,N-dimethyl-tryptamine) is incubated with a preparation of rat brain mitochondria. The colour is apparently not dependent on oxygen for its formation, is associated only with the particulate matter and cannot be brought into solution by treatment with various organic solvents, detergents, acid or alkali. The reaction is inhibited (80 per cent) by EDTA.


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LEVINE, W. Formation of Blue Oxidation Product from Psilocybin. Nature 215, 1292–1293 (1967).

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