Abstract
Antibody forming cells express one of two codominant alleles in the case of allotypes and perhaps of other traits connected with the formation of immunoglobulin. That this property does not apply to all genetic systems of these cells is demonstrated by the presence of both parental histocompatibility antigens in heterozygous immunocytes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Pernis, B., Chiappino, G., Kelus, A. S., and Gell, P. G. H., J. Exp. Med., 122, 853 (1965).
Cebra, J. J., Colberg, J. E., and Dray, S., J. Exp. Med., 123, 547 (1966).
Chiappino, G., and Pernis, B., Path. Microbiol., 27, 8 (1964).
Pernis, B., in Genetic Variation in Somatic Cells, proc. of a symposium 209 (Academia, Prague, 1966).
Lieberman, R., and Potter, M., J. Mol. Biol., 18, 516 (1966).
Kunkel, H. G., Yount, W. J., and Litwin, S. D., Science, 154, 1041 (1966).
Bentler, E., Cold Spring Harbor Symp. Quant. Biol., 29, 261 (1964).
Russel, L. B., Science, 133, 1795 (1961).
Lyon, M. E., Nature, 190, 372 (1961).
Ohno, S., Weiler, C., Poole, J., Christian, L., and Stenius, C., Chromosoma, 18, 177 (1966).
Celada, F., J. Exp. Med., 124, 1 (1966).
Celada, F., and Makinodan, T., J. Immunol., 86, 638 (1961).
Snell, G. D., Transplantation Bull., 2, 6 (1955).
Celada, F., and Rotman, B., Proc. US Nat. Acad. Sci., 57, 630 (1967).
Rotman, B., and Papermaster, B. W., Proc. US Acad. Sci., 55, 134 (1966).
Jerne, N. K., and Nordin, A. A., in Cell Bound Antibodies, 109 (Wistar Institute Press, Philadelphia, 1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CELADA, F., KLEIN, G. Autonomy of H-2 Genes in Individual Immunocytes. Nature 215, 1136–1139 (1967). https://doi.org/10.1038/2151136a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2151136a0
This article is cited by
-
Targeting the B7 Family of Co-Stimulatory Molecules
BioDrugs (2013)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.