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Virus Induced Point Mutation

Abstract

VIRUS particles have been shown to induce chromosome breakage in mammalian tissue culture1–4. If it were a property of viruses to break chromosomes, then one would expect viruses to cause point mutation which would result from errors in the genetic code at the site where the chromosome was broken and reconstituted. With this reasoning, experiments were undertaken to determine whether viruses induce point mutation in the form of recessive lethal mutation on the X chromosome of Drosophila melanogaster. The virus used was Sigma—an organism which causes sensitivity to carbon dioxide5.

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BAUMILLER, R. Virus Induced Point Mutation. Nature 214, 806–807 (1967). https://doi.org/10.1038/214806a0

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  • DOI: https://doi.org/10.1038/214806a0

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