Letter | Published:

Reciprocal in toto Conversion of Mycobacterium phleiMycobacterium smegmatis by Mediation of an Intermediate Hybrid Genome : B2h

Naturevolume 214pages518520 (1967) | Download Citation

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Abstract

PHAGE B2h has been obtained from lysogenic complexes formed between M. phlei and phage phlei B2 (ref. 1). Phage B2h has shown in addition to host range alteration (h) changes in plating efficiency, immunity, serology, plaque and electron microscopic morphology as compared with wild phage B2 (refs. 2 and 3). It was suggested that such major changes resulting in B2h were caused by recombination between phage B2 genome and a chromosomal segment of M. phlei (F89 or SN109 respectively).

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References

  1. 1

    Juhasz, S. E., and Bönicke, R., Nature, 210, 1185 (1966).

  2. 2

    Juhasz, S. E., and Bönicke, R., Symposium on Mycobacterial Variation, Borstel, West Germany, October 13–15, 1965 (in the press).

  3. 3

    Juhasz, S. E., and Bönicke, R., Canad. J. Microbiol., 11, 235 (1965).

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  1. 3962 West 10th Avenue, Vancouver, B.C., Canada

    • S. E. JUHASZ

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https://doi.org/10.1038/214518a0

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