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Identity and Significance of Some Pink Spots in Schizophrenia and Other Conditions

Naturevolume 214pages484485 (1967) | Download Citation

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Abstract

3,4-DIMETHOXYPHENYLETHYLAMINE (DMPE) has been claimed to be present in the urines of many schizophrenic patients1–5. DMPE gives a pink spot on paper chromatograms developed first with ninhydrin and then treated with Ehrlich reagent (p-dimethylaminobenzaldehyde)6. Others have assumed that pink spots found on chromatograms of the urines of schizophrenics are DMPE7–10.

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References

  1. 1

    Friedhoff, A. J., and Van Winkle, E., Nature, 194, 897 (1962).

  2. 2

    Takesada, M., Kakimoto, Y., Sano, I., and Kaneko, Z., Nature, 199, 203 (1963).

  3. 3

    Sen, N. P., and McGeer, P. L., Biochem. Biophys. Res. Commun., 14, 227 (1964).

  4. 4

    Kuehl, F. A., Hichens, M., Ormond, R. E., Meisinger, M. A. P., Gale, P. H., Cirillo, V. J., and Brink, N. G., Nature, 203, 154 (1964).

  5. 5

    von Studnitz, W., and Nyman, G. E., Acta Psychiat. Scand., 41, 117 (1965).

  6. 6

    Friedhoff, A. J., and Van Winkle, E., J. Chromatog., 11, 272 (1963).

  7. 7

    Bourdillon, R. E., Clarke, C. A., Ridges, A. P., Sheppard, P. M., Harper, P., and Leslie, S. A., Nature, 208, 453 (1965).

  8. 8

    Lancet, ii, 1169 (1965).

  9. 9

    Brit. Med. J., i, 119 (1966).

  10. 10

    Calbiochem Catalog, Los Angeles, California, 25 (1966).

  11. 11

    Perry, T. L., Hansen, S., and Macintyre, L., Nature, 202, 519 (1964).

  12. 12

    Perry, T. L., Hansen, S., MacDougall, L., and Schwarz, C. J., Nature, 212, 146 (1966).

  13. 13

    Perry, T. L., Hestrin, M., MacDougall, L., and Hansen, S., Clin. Chim. Acta, 14, 116 (1966).

  14. 14

    Perry, T. L., and Schroeder, W. A., J. Chromatog., 12, 358 (1963).

  15. 15

    Lindqvist, B., and Storgårds, T., Acta Chem. Scand., 7, 87 (1953).

  16. 16

    Tabor, C. W., Tabor, H., and Bachrach, U., J. Biol. Chem., 239, 2194 (1964).

  17. 17

    Perry, T. L., Hansen, S., Hestrin, M., and Macintyre, L., Clin. Chim. Acta, 11, 24 (1965).

  18. 18

    Technicon Chromatography Corporation, Chauncey, N. Y., technical bulletin (1965).

  19. 19

    Kakimoto, Y., and Armstrong, M. D., J. Biol. Chem., 237, 208 (1962).

  20. 20

    Perry, T. L., Shaw, K. N. F., Walker, D., and Redlich, D., Pediatrics, 30, 576 (1962).

  21. 21

    Faurbye, A., and Pind, K., in Sct. Hans Hospital, 150 Years Anniversary, 136 (Munksgaard, Copenhagen, 1966).

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Affiliations

  1. Department of Pharmacology, University of British Columbia, Vancouver, 8, Canada

    • THOMAS L. PERRY
    • , SHIRLEY HANSEN
    •  & LYNNE MACDOUGALL

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https://doi.org/10.1038/214484a0

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