Abstract
3,4-DIMETHOXYPHENYLETHYLAMINE (DMPE) has been claimed to be present in the urines of many schizophrenic patients1–5. DMPE gives a pink spot on paper chromatograms developed first with ninhydrin and then treated with Ehrlich reagent (p-dimethylaminobenzaldehyde)6. Others have assumed that pink spots found on chromatograms of the urines of schizophrenics are DMPE7–10.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Friedhoff, A. J., and Van Winkle, E., Nature, 194, 897 (1962).
Takesada, M., Kakimoto, Y., Sano, I., and Kaneko, Z., Nature, 199, 203 (1963).
Sen, N. P., and McGeer, P. L., Biochem. Biophys. Res. Commun., 14, 227 (1964).
Kuehl, F. A., Hichens, M., Ormond, R. E., Meisinger, M. A. P., Gale, P. H., Cirillo, V. J., and Brink, N. G., Nature, 203, 154 (1964).
von Studnitz, W., and Nyman, G. E., Acta Psychiat. Scand., 41, 117 (1965).
Friedhoff, A. J., and Van Winkle, E., J. Chromatog., 11, 272 (1963).
Bourdillon, R. E., Clarke, C. A., Ridges, A. P., Sheppard, P. M., Harper, P., and Leslie, S. A., Nature, 208, 453 (1965).
Lancet, ii, 1169 (1965).
Brit. Med. J., i, 119 (1966).
Calbiochem Catalog, Los Angeles, California, 25 (1966).
Perry, T. L., Hansen, S., and Macintyre, L., Nature, 202, 519 (1964).
Perry, T. L., Hansen, S., MacDougall, L., and Schwarz, C. J., Nature, 212, 146 (1966).
Perry, T. L., Hestrin, M., MacDougall, L., and Hansen, S., Clin. Chim. Acta, 14, 116 (1966).
Perry, T. L., and Schroeder, W. A., J. Chromatog., 12, 358 (1963).
Lindqvist, B., and Storgårds, T., Acta Chem. Scand., 7, 87 (1953).
Tabor, C. W., Tabor, H., and Bachrach, U., J. Biol. Chem., 239, 2194 (1964).
Perry, T. L., Hansen, S., Hestrin, M., and Macintyre, L., Clin. Chim. Acta, 11, 24 (1965).
Technicon Chromatography Corporation, Chauncey, N. Y., technical bulletin (1965).
Kakimoto, Y., and Armstrong, M. D., J. Biol. Chem., 237, 208 (1962).
Perry, T. L., Shaw, K. N. F., Walker, D., and Redlich, D., Pediatrics, 30, 576 (1962).
Faurbye, A., and Pind, K., in Sct. Hans Hospital, 150 Years Anniversary, 136 (Munksgaard, Copenhagen, 1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PERRY, T., HANSEN, S. & MACDOUGALL, L. Identity and Significance of Some Pink Spots in Schizophrenia and Other Conditions. Nature 214, 484–485 (1967). https://doi.org/10.1038/214484a0
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1038/214484a0
This article is cited by
-
Monoacylcadaverines as substrates for both monoamine oxidase and diamine oxidase; low rates of activity
Experientia (1980)
-
Cadaverine in the brain of axenic mice
Nature (1974)
-
Biochemical Research in Schizophrenia
Nature (1971)
-
Urine Volume and Pink Spots in Schizophrenia and Health
Nature (1969)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.