Letter | Published:

Effect of Coffee and Tea on Serum Lipids in the Rat

Naturevolume 214pages426427 (1967) | Download Citation

Subjects

Abstract

WE report experiments designed to distinguish the effects of the beverage and of sugar on the blood lipids of rats. Epidemiological investigations1,2 have already shown an association between ischaemic heart disease and the taking of coffee. Acute experiments in man and dogs3,4 indicate that caffeine produces a rise in free fatty acids in the blood, but no change in cholesterol or triglycerides. Our own investigations with patients5, however, suggest that the association of heart disease with coffee (or tea) is more likely to be caused by the sugar taken with the coffee or tea than by the caffeine they contain.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Paul, O., Lepper, M. H., Phelan, W. H., Dupertins, G. W., MacMillan, A., McKean, H., and Park, H., Circulation, 28, 20 (1965).

  2. 2

    Little, J. A., Shanoff, H. M., Csima, A., Redmond, S. E., and Yano, R., Lancet, i, 933 (1965).

  3. 3

    Bellet, S., Kershbaum, A., and Aspe, J., Arch. Intern. Med., 116, 750 (1965).

  4. 4

    Bellet, S., Aspe, J., Kershbaum, A., and Zanuttini, D., Circulation, 30, 45 (1964).

  5. 5

    Yudkin, J., and Roddy, J., Lancet, ii, 6 (1964).

  6. 6

    Expert Panel Methodology Manual, Section V, 1.

  7. 7

    Zlatkis, A., Zak, B., and Boyle, G. J., J. Lab. Clin. Med., 41, 486 (1953).

  8. 8

    King, E. J., and Allott, E. N., Recent Adv. in Clin. Path., second edition (edit. by Dykes, S. C.), 271 (Churchill, London, 1952).

  9. 9

    Stern, I. S., and Shapiro, B., J. Clin. Pathol., 6, 158 (1953).

  10. 10

    Albrink, M. T., J. Lipid Res., 1, 53 (1959).

  11. 11

    Mann, H. B., and Whitney, D. R., Ann. Math. Statist., 18, 50 (1947).

  12. 12

    Yudkin, J., and Morland, J., Amer. J. Clin. Nutrit. (in the press, 1967).

Download references

Author information

Affiliations

  1. Queen Elizabeth College, University of London

    • P. AKINYANJU
    •  & JOHN YUDKIN

Authors

  1. Search for P. AKINYANJU in:

  2. Search for JOHN YUDKIN in:

About this article

Publication history

Received

Revised

Issue Date

DOI

https://doi.org/10.1038/214426b0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.