Letter | Published:

Cytomegalovirus Type Cytopathic Changes in Spontaneously Degenerating Human Embryonic Cell Cultures

Naturevolume 214pages419420 (1967) | Download Citation



INTRA-UTERINE infections caused by cytomegaloviruses can cause pregnancy wastage by abortion or the delivery of macerated stillborn foetuses1. Cytomegalic inclusion disease is rare and the mother of the afflicted foetus is asymptomatic, so that a virological approach to this problem is difficult; the causative agents were never recovered from concepti. Cytomegaloviruses, however, have been isolated from children with occult infection, by means of in vitro cultivation of cells from various organs, mainly adenoids4 and kidneys2. This communication deals with accidental recovery of an agent causing cytomegalovirus type cytopathic effect from cell cultures derived from human embryonic tissues.

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  1. 1

    Belter, L. F., and Camillo, M., Amer. J. Obstet. Gynec., 78, 1243 (1959).

  2. 2

    Benyesh-Melnick, M., Rosenberg, S. H., and Watson, B., Proc. Soc. Exp. Biol., 117, 452 (1964).

  3. 3

    Diosi, P., Babusceac, L., Nevinglovschi, O., and Stoicanescu, A., Path. et Microbiol., 28, 513 (1966).

  4. 4

    Rowe, W. P., Hartley, J. W., Waterman, S., Turner, H. C., and Huebner, R. J., Proc. Soc. Exp. Biol., 92, 418 (1956).

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  1. Department of Epidemiology, Institute of Hygiene, Timisoara, Roumania



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