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Persistence of Syngeneic Preference given by a Methylcholanthrene-induced Sarcoma after Four Consecutive Passages in F1 Hybrids

Abstract

MURINE tumours of syngeneic origin sometimes show deficient growth when transplanted in F1 hybrids of the parental strain and some other strain. This has been found with immunologically competent tissue tumours1,2, sarcomata induced by carcinogens3,4 and spontaneous mammary carcinomata3, but must not be considered as a general feature of all murine syngeneic tumours (ref. 5 and personal communication from H. D. Suit).

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OTH, D., BURG, C. Persistence of Syngeneic Preference given by a Methylcholanthrene-induced Sarcoma after Four Consecutive Passages in F1 Hybrids. Nature 214, 418–419 (1967). https://doi.org/10.1038/214418a0

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