Letter | Published:

Nδ-(2d-amino-2-carboxyethyl)-ornithine, a New Amino-acid from Alkali-treated Proteins

Naturevolume 214pages404405 (1967) | Download Citation



A NEW amino-acid, N ε-(2-amino-2-carboxyethyl)-lysine, in acid hydrolysates of alkali-treated proteins has been reported1,2. The trivial name lysinoalanine was chosen for this compound, which is probably formed by the addition of an amino group of a lysyl residue at the double bond of a dehydroalanyl residue formed after alkaline decomposition of disulphide bonds. Lysinoalanine has been synthesized by two different methods1,3 in order to confirm its chemical structure.

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  1. 1

    Bohak, Z., J. Biol Chem., 239, 2878 (1964).

  2. 2

    Ziegler, Kl., J. Biol. Chem., 239, PC 2713 (1964).

  3. 3

    Okuda, T., and Zahn, H., Chem. Ber., 98, 1164 (1965).

  4. 4

    Spackman, D. H., Stein, W. H., and Moore, S., Anal. Chem., 30, 1190 (1958).

  5. 5

    Mellet, P., and Swanepoel, O. A., Naturwissenschaften, 52, 495 (1965).

  6. 6

    Mellet, P., and Louw, D. F., Chem. Comm., 17, 396 (1965).

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  1. Deutsches Wollforschungsinstitut an der Technischen Hochschule, Aachen

    • , I. MELCHERT
    •  & C. LÜRKEN


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