Letter | Published:

Intramitochondrial pH: a Statistical Question of Hydrogen Ion Concentration in a Small Element of Space-time

Naturevolume 214page400 (1967) | Download Citation

Subjects

Abstract

McCABE1 has argued, on statistical grounds, that the pH within mitochondria is ill-defined. In the process he asserts that water at pH 7 contains about 30 hydrogen ions per µ3, but, in fact, the value is more nearly 60 hydrogen ions per µ3 (ref. 2).

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    McCabe, M., Nature, 213, 280 (1967).

  2. 2

    Peters, R. A., J. State Med., 37, 1 (1929). Netter, H., Pflügers Arch. Ges. Physiol., 234, 680 (1934).

  3. 3

    Lindsay, R. B., and Margenau, H., Foundations of Physics, 178 (Wiley, New York, 1936); Hill, T. L., Thermodynamics of Small Systems, Part I, 3 (Benjamin, New York, 1963).

  4. 4

    Mitchell, P., and Moyle, J., Nature, 208, 147 (1965).

  5. 5

    Chance, B., and Mela, L., Nature, 212, 369 (1966).

  6. 6

    Eigen, M., and de Maeyer, L., Z. Elektrochem., 59, 986 (1955).

  7. 7

    Bell, R. P., The Proton in Chemistry (Methuen, London, 1959).

  8. 8

    Edsall, J. T., in Proteins, Amino Acids and Peptides (edit. by Cohn, E. J., and Edsall, J. T.), 465 (Reinhold, New York, 1943).

  9. 9

    Davies, J. T., and Rideal, E. K., Interfacial Phenomena, second ed., 94 (Academic Press, New York, 1963).

Download references

Author information

Affiliations

  1. Glynn Research Laboratories, Bodmin, Cornwall

    • PETER MITCHELL

Authors

  1. Search for PETER MITCHELL in:

About this article

Publication history

Received

Revised

Issue Date

DOI

https://doi.org/10.1038/214400a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.