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Induction of 19S Antibody Synthesis without Stimulation of Cellular Proliferation

Naturevolume 214pages293295 (1967) | Download Citation

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Abstract

ANTIGEN evokes a heterogeneous immunoglobulin response in which each molecular species is probably synthesized by a different cell population1,2. Although recent reports3–8 have suggested that antigen stimulates both proliferation and antibody synthesis in the same lymphoid cell, these two functions may not necessarily be associated in all the types of cells which respond to antigen. This possibility was examined in cells making 19S antibody—one of the four antibody classes known in the mouse9.

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  1. Section of Clinical Immunology, New England Medical Center Hospitals, Boston, Massachusetts

    • WALTER J. K. TANNENBERG

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https://doi.org/10.1038/214293a0

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